Oral Candidiasis

exp date isn't null, but text field is

This is a fungal infection of the oral mucosa caused by Candida infection, mainly Candida albicans. 

Clinical presentation  Features of candidiasis are divided according to the types as follows: 

Pseudomembranous 

  • White creamy patches/plaque
  • Cover any portion of mouth but more on tongue, palate, and buccal mucosa
  • Sometimes  may  present  as  erythematous  type  whereby  bright  erythematous  mucosal lesions with only scattered white patches/plaques

Hyperplastic 

  • White patches leukoplakia-like which are not easily rubbed-off

Angular cheilitis (angular stomatitis) 

  • Soreness, erythema and fissuring at the angles of the mouth
  • Commonly associated with denture mastitis but may represent a nutritional deficiency or it may be related to orofacial granulomatosis or HIV infection

Pharmacological Treatment 

A:  nystatin  suspension  (PO)  100,000IU  (1  ml)  mixture  held  in  the  mouth  for  at  least 3minutes before swallowing, 6hourly  

OR 

C:  miconazole  gel  (PO)  25mg/ml  5–10mls  in  mouth: hold  in  the  mouth  for  60  seconds before swallowing. The treatment should be continued for 5days after cure/clearance. Where topical  application has failed, or candida infection has been considered severe, use: 

A: fluconazole (PO) 150mg 24hourly for 7days 

OR  

D: itraconazole (PO) 200mg 24hourly for 7days 

Note: Candidiasis has several risk factors. It is recommended that for HIV/AIDS patients with candidiasis, refer to the Tanzania HIV/AIDS Guidelines.