Herpes Simplex Keratitis

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It is an inflammatory condition of the cornea caused by Herpes Simplex Virus. 

Clinical presentation 

• Acute unilateral painful eye
• Blurring of vision
• Reduced corneal sensation
• Dendritic corneal ulcer seen on staining with fluorescein

Investigations 

• Visual acuity
• Slit lamp bimicroscopy
• Fluorescein staining

Pharmacological Treatment 

C:  acyclovir  3%,  ophthalmic  ointment  inserted  in  the  lower  conjunctival  sac,  4hourly. Continue for 3days after ulcer has been healed. 

AND 

B: acyclovir, (PO), 400mg 8–4hourly a day for 7–10days depending on initial response as well as the extent of the ulcer. 

Note: Topical corticosteroids are contraindicated in the treatment of dendritic ulcers