Genital Ulcer Disease (GUD)

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GUD  is  a  loss  of  continuity  of  skin  or  mucous  membrane  producing  one  or  more  lesions  in  the  genital area.  

Causes 

• Treponema pallidum
• Haemophilus ducreyi
• Chlamydia trachomatis  
• Herpes simplex virus type 2 (HSV) 
• Calymmatobacterium granulomatis

Clinical presentation 

• Ulcer 
• Sore 
• Vesicle 

Investigation(s) if the HF has a Laboratory capable of doing:  

• Wet preparation 
• Gram stain   
• Culture and Sensitivity 
• Fluorescent Microscopy 
• Treponema palladium particle agglutination (TPPA) 
• Rapid Plasma Reagin (RPR) 
• ELISA 
• Quantitative or qualitative PCR  
• Genetic sequencing 

Management and Treatment of GUD (see flow chart 12.7)