Strongyloidiasis

exp date isn't null, but text field is

Strongyloidiasis is a chronic parasitic infection of humans caused by Strongyloides stercoralis. Without appropriate therapy, the infection does not resolve and may persist for life. In cases of immunodeficiency, it may be severe or even life-threatening.

Causes

• Stronglyloides stercoralis

Signs and symptoms:

Acute

• Lower extremity itch
• Cough, dyspnoea, wheezing
• Low grade fever
• Epigastric discomfort, diarrhoea, occasional nausea, and vomiting

Chronic

• Vague abdominal discomfort
• Abdominal pain – burning, cramping
• Intermittent diarrhoea
• Weight loss
• Occasional nausea and vomiting
• Recurrent rashes

Investigations

• Stool for occult blood, ova and parasites

Pharmacological treatment

Albendazole oral

Adult:

400 mg every 12 hours for 3 days

Repeat after 3 weeks if necessary

Child:

2 – 17 years: 400 mg every 12 hours for 3 days

Repeat after 3 weeks if necessary

Ivermectin oral

Adult:

200 mcg/kg/day for 2 days

First trimester of pregnancy: Not recommended             

Repeat at 6 to 12-month interval depending on symptoms

Child:

5 -17 years: 150 mcg/kg/day as a single dose

Under 5 years: Not recommended                                       

Repeat at 6 to 12-month interval depending on symptoms