Plague (Bubonic)

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Case definition: Any person with rapid onset of fever, chills, headache, severe malaise, prostration with extremely painful swelling of lymph nodes, or cough with blood-stained sputum, chest pain and difficulty in breathing in an area known to have plague.

Treat with:

 

Medicine

Adult Dose

Frequency

Duration

 

streptomycin im

1g

0.5g

Paed = 5-10mg/kg

first dose

6 hourly

then

10 days

or

chloramphenicol im/iv

12.5-25mg/kg

Paed = 6.25–12.5mg/kg

6 hourly

10 days

Prophylaxis whilst nursing & contacts:

Medicine

Adult Dose

Frequency

Duration

Doxycycline po

100mg

2 times a day

10 days