Anthrax (Cutaneous)

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Case definition: an acute bacterial disease caused by Bacillus anthracis (Gram-positive). It is manifested at first by itching of an exposed skin surface, followed by a painful lesion which becomes papular, then vesiculated and eventually develops into a depressed black eschar in 2-6 days.

NB Do not take any laboratory specimens, treat on clinical and epidemiological basis.

Initial treatment, in severe cases:

 

Medicine

Adult dose

Frequency

Duration

 

benzylpenicillin im/iv

1-2MU

4 times a day

initially

then

procaine penicillin im

3gm

once daily

7-10 days

 

Less severe cases:

Medicine

Adult Dose

Frequency

Duration

Doxycycline po*

200mg first dose, then 100mg

once daily

7 days

*avoid use of doxycycline in pregnant women and children

NB: Pulmonary form of Anthrax- refer to designated Infectious Disease Hospital