Intestinal Obstruction

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See full Zimbabwe STG for full management. 

Antibiotic use in intestinal obstruction is necessary where bacterial translocation is suspected especially with longer history of obstruction or where a closed loop obstruction with possible gangrene/perforation of bowel is suspected e.g in sigmoid volvulus or at surgery where unprepared bowel is opened. 

First line: 

 

Medicine

Dose

Frequency

 

benzyl penicillin iv

2.5MU

4 times a day

and

gentamicin iv

120mg

once a day

and

metronidazole iv

500mg

3 times a day

Second Line

 

Medicine

Dose

Frequency

 

ceftriaxone iv

1g

2 times a day

and

metronidazole iv

500mg

3 times a day

NB Gentamicin should not be used where renal impairment is likely or confirmed.