Antimicrobial Dosages for Children and Infants Over 2 Months

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For dosages for non antimicrobial medicines see full Zimbabwe STG

  • For infants under one month see Neonatal Conditions
  • Read the dosage column carefully in conjunction with the "doses/day" column
  • Do not exceed the adult dose; the dosage per kg is not applicable for children >40kg

Medicine

Route

Dose

Frequency

Amoxicillin

125mg/5mL syrup

po

16mg/kg

8 hourly

Ampicillin

500mg injection

im/iv

mild 12.5mg/kg

severe 25mg/kg

6 hourly

Benzylpenicillin

3g injection = 5MU

iv/im

50,000 – 100,000u/kg

(0.05 – 0.1MU/kg)

6 hourly

Chloramphenicol

1g injection; 125mg/5ml syrup

iv/im/po

mild 12.5mg

severe (meningitis) 25mg/kg

6 hourly

Clindamycin

75mg/5mL syrup; 250mg capsule; 1g injection

po/im

mild 4mg/kg

severe 10mg/kg

6 hourly

Cloxacillin

125mg/5ml syrup; 250mg capsule; 0.5g injection

iv/im/po

12.5 to 25mg/kg

6 hourly

Cotrimoxazole

120mg tab; 480mg tab; 240mg/5ml syrup

po

normal dose 30mg/kg

12 hourly

high dose 60mg/kg

Erythromycin

125mg/5mL syrup

po

6.25 to 12.5mg/kg

6 hourly

Ethambutol

100mg dispersible tablet

po

15mg/kg

once a day

Gentamicin

20mg/ml injection; 40mg/ml injection

iv/im

7.5mg/kg

once a day

Griseofulvin

125mg/5ml syrup; 125mg tablet; 500mg tablet

po

5mg/kg

12 hourly

Isoniazid

100mg tablet

po

10mg to 20mg/kg

once a day

Kanamycin

1g injection

im

7.5mg/kg

12 hourly

Ketoconazole

200mg tab; 100mg/5ml

po

5 to 10mg/kg

once a day

Metronidazole

200mg tab; 1g suppository; 5mg/ml injection; 200mg/5ml syrup

pr/iv

severe anaerobic inf 7.5mg/kg

8 hourly

po

intestinal amoebiasis 10mg/kg

po

giardiasis 5mg/kg

Nitrofurantoin

50mg tab

po

1.5mg/kg (age >3 month)

4 times a day

Penicillin V

125mg/5ml syrup

250mg tablet

po

12.5mg/kg

6 hourly

Procaine Penicillin

300mg/ml injection

im

50mg/kg

once a day

Rifampicin

300mg cap; 100mg/5ml syrup

po

10 to 20mg/kg

daily