Liver Abscess

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Consider when there is right upper quadrant pain, fever and hepatomegaly. Could be a pyogenic liver abscess or amoebic abscess. Surgical or percutaneous drainage should be part of treatment, together with antibiotics. If use of antibiotics without drainage is unavoidable, long course of antibiotics with serial scans and close supervision will be required.

For abscesses threatening to rupture through lobe of liver, skin or diaphragm, aspirate in conjunction with medicine therapy.

Pyogenic Abscess:

  Medicine Adult Dose  Frequency Duration
  metronidazole iv  500mg 3 times a day 4-6 weeks
plus
 ampicillin iv 1g  4 times a day 4-6 weeks
or ceftriaxone iv 1g once a day 4-6 weeks
or ciprofloxacin po 500mg twice a day 4-6 weeks

Amoebic Abscess:

Medicine

Dose

Frequency

Duration

Metronidazole po

400mg

3 times a day

7-10 days