Liver Abscess
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Consider when there is right upper quadrant pain, fever and hepatomegaly. Could be a pyogenic liver abscess or amoebic abscess. Surgical or percutaneous drainage should be part of treatment, together with antibiotics. If use of antibiotics without drainage is unavoidable, long course of antibiotics with serial scans and close supervision will be required.
For abscesses threatening to rupture through lobe of liver, skin or diaphragm, aspirate in conjunction with medicine therapy.
Pyogenic Abscess:
Medicine | Adult Dose | Frequency | Duration | |
metronidazole iv | 500mg | 3 times a day | 4-6 weeks | |
plus |
ampicillin iv | 1g | 4 times a day | 4-6 weeks |
or | ceftriaxone iv | 1g | once a day | 4-6 weeks |
or | ciprofloxacin po | 500mg | twice a day | 4-6 weeks |
Amoebic Abscess:
Medicine |
Dose |
Frequency |
Duration |
Metronidazole po |
400mg |
3 times a day |
7-10 days |