Poliomyelitis

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An acute viral infection characterised by acute onset of flaccid paralysis of skeletal muscles. It is transmitted from person to person through the faecal-oral route. Poliomyelitis is a notifiable disease.

Cause

Polio virus (enterovirus) types I, II, and III

Clinical features

  • Majority of cases are asymptomatic, only 1% result in flaccid paralysis
  • Non paralytic form: minor illness of fever, malaise, headache, and vomiting, muscle pains, spontaneous recovery in 10 days
  • Paralytic form: after the aspecific symptoms, rapid onset (from morning to evening) of asymmetric flaccid paralysis, predominantly of the lower limbs, with ascending progression
  • Paralysis of respiratory muscles is life threatening (bulbar polio)
  • Aseptic meningitis may occur as a complication

Differential diagnosis

  • Guillain-Barré syndrome
  • Traumatic neuritis
  • Transverse myelitis
  • Pesticides and food poisoning

Consider all cases of Acute Flaccid Paralysis as possible Poliomyelitis: alert the district focal person for epidemic control, and send 2 stool samples (refrigerated).

Investigations

  • Isolation of the virus from stool samples
  • Viral culture
  • Ensure that Giardia intestinalis, Entamoeba histolytica, Cryp- tosporidium, Cyclospora, sarcocystis, Toxoplasma gondii are included in the investigations

Management

Treatment LOC

Acute Stage

  • Poliomyelitis in this stage without paralysis is difficult to diagnose

Paralytic form

  • If paralysis is recent, rest the patient completely 
  • Note: Do not give IM injections as they make the paralysis worse
  • Refer the patient to a hospital for supportive care
  • After recovery (if partially/not immunised), complete recommended immunisation schedule

Chronic stage

  • Encourage active use of the limb to restore muscle function/physiotherapy
  • In event of severe contractures, refer for corrective surgery
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Prevention

  • Isolate patient for nursing and treatment, applying contact and droplets precautions
  • Immunise all children below 5 years from the area of the suspected case
  • If case is confirmed, organize mass immunisation campaign
  • Proper disposal of children’s faeces
  • Immunisation (see Immunizations)
  • Proper hygiene and sanitation