Hepatitis B Vaccination

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  • Since 2005, children are immunised against Hepatitis B in the routine childhood immunization using the DPT-HepB- Hib vaccine at 6, 10, and 14 weeks of age
  • For adolescents and adults, it is recommended that the hepatitis B vaccination is given preferably after testing for hepatitis B infection (HBsAg and Anti-HBs). Patients with HIV and pregnant women should be handled on a case by case basis
  • Vaccination is recommended for high risk groups, e.g:
    • Health workers in clinical settings and training
    • Intravenous drugs users
    • Persons who frequently receive blood transfusions
    • Recipients of solid organ transplantation
    • High-risk sexual behaviour
    • Partners and household contacts of HBsAg positive patients
    • Support staff in health facilities
  • The schedule has three doses: at 0, 1 month after 1st dose, and 6 months after first dose (0, 1, 6 months)
  • The storage temperature for the vaccine is 2°C to 8°C
  • Dose: 0.5 mL given intramuscularly on the deltoid muscle (upper arm)
  • Do NOT give vaccine on the buttocks because of low immune response (decreased protective antibody response) and risks of injury to the sciatic nerve