Refers to conjunctival infection of neonates by STI organisms in the infected mother’s birth canal. It is a very serious condition that can lead to corneal ulceration and ultimately to blindness. Blindness in children is associated with high infant morbidity and mortality.
Causes
- Commonly caused by Neisseria gonorrhoeae and Chlamydia trachomatis
- Other non-STI causes of neonatal conjunctivitis predisposed by difficult labour such as early rupture of membranes, vacuum extraction or other assisted vaginal delivery
Clinical features
- Purulent discharge from one or both eyes within 30 days from birth
- Inflamed and swollen eyelids
- Complications of untreated conjuctivitis: corneal ulceration, perforation, scarring and blindness
Investigations
- Pus swab: Gram stain, Culture & Sensitivity
Management
Treatment should cover both gonorrhoea and chlamydia
- Start cleaning with normal saline and apply tetracycline ointment every hour while referring for systemic treatment
- Ceftriaxone 125 mg single dose IM plus azithromycin syrup 20 mg/kg orally, once daily for 3 days
- Irrigate the eyes with saline or sterile water
- Use gloves and wash hands thoroughly after handling the eyelids
- Cover the eye with gauze while opening the eyelid as pus may be under pressure
- Topical tetracycline eye ointment has NO added benefit in active disease
- Treat both parents for Gonorrhoea and Chlamydia and screen for HIV and syphilis
Prevention
- Screen and treat all infected mothers in antenatal care
- Apply prophylactic tetracycline eye ointment 1% to both eyes of ALL newborns at the time of delivery