Herpes Simplex

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It is an acute viral infection caused by Herpes simplex virus hominis (types HSV1, HSV2 acquired by close contact with an infected individual 

Clinical presentation 

• Preceding tingling sensation, discomfort and itching
• Grouped  vesicles  forming  on  the  skin,  and  mucous  membranes,  particularly  the buccal area, genitalia, conjunctivae, and cornea 
• Eczema herpeticum – herpes simplex infection in Atopic Eczema patients. 

Pharmacological Treatment 

B: acyclovir cream (topical) applied 4hourly for 7–10days 

OR (especially if severe) 

B: acyclovir (PO) 200mg 6hourly for 7–10days 

For recurrent cases  

B: acyclovir (PO) 400mg 12hourly for 6months up to 1year

Note: Benefit of systemic acyclovir is optimum when given within the first 72hours of onset of symptoms