Sickle Cell Disease (SCD) - prophylaxis and immunisation against pneumococcal infection

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Prophylaxis against Pneumococcal Infection
A: phenoxymethyl penicillin (PO) 125mg for children younger than 3years; phenoxymethyl penicillin (PO) 250mg for children 3 years and older twelve hourly until 5years of age in all children with SCA.

Immunisation against pneumococcal infection
A: pneumococcal conjugate vaccine (PCV-13) from two months of age, 3 doses 8 weeks apart (i.e at age 2months, 4 months and 6 months) and a booster dose between 12-15 months. If the child has not previously received this vaccine, then at least one dose should be given between 6-18 years. PCV-13 and vaccine against H. influenza is incorporated in Tanzania EPI schedule.

S: pneumococcal polysaccharide vaccine (PPSV-23) - at 2 years then after every 5 years for life.