Acute Epididymo-orchitis (Painful Scrotal Swelling)

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This is an inflammation of the epididymis and testis characterized by scrotal pain, tenderness and swelling of less than 6 weeks’ duration.

Causes

STI-related

Chlamydia trachomatis

Neisseria gonorrhoeae

Treponema pallidum

Non-STI-related

Testicular torsion

Tuberculosis

Mumps orchitis

Tumours

Signs and symptoms

  • Fever
  • Unilateral swelling and inflammation of the epididymis, +/- testicle
  • Urethral discharge
  • Increased frequency of micturition
  • Hydrocele
  • Scrotal pain

Complications

  • Scrotal abscess and pyocele
  • Fertility problems
  • Testicular atrophy

Investigations

  • Urinalysis
  • Urine microscopy, culture and sensitivity
  • Ultrasound scan of the scrotum

Treatment objectives

  • Relieve pain
  • Identify and treat underlying causes

Non-pharmacological treatment

  • Bed rest
  • Scrotal support until inflammation and fever subsides

Pharmacological treatment

Sexually transmitted Chlamydia and Gonorrhoea:

Ceftriaxone IM

250 mg as a single dose

PLUS

Doxycycline oral

100 mg two times daily for 10 days 

Sexually transmitted Chlamydia, Gonorrhoea and Enteric organisms (e.g. in men who practice insertive anal sex):

Ceftriaxone

250 mg IM as a single dose

PLUS

Ciprofloxacin

500 mg two times daily for 10 days

Enteric organisms:

Ciprofloxacin

500 mg two times daily for 10 days

For pain:

Ibuprofen

400 mg two times daily for 10 days

 Referral  If no improvement after the above treatment refer for specialist care