Prostatitis
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Prostatitis is an infection or inflammation of the prostate gland. Prostatitis is categorized as follows:
Category |
|
Characteristics |
Signs and Symptoms |
||
|
|
Pain |
Bacteria |
WBCs |
|
I |
Acute prostatitis |
- Bacterial infection of the prostate gland - Requires urgent medical treatment. |
Yes |
Yes |
Yes |
II |
Chronic bacterial prostatitis |
- Rare - Intermittent urinary tract infections |
± |
Yes |
Yes |
IIIa |
Inflammatory |
- Chronic prostate inflammation - Chronic pain - 90%-95% of prostatitis diagnoses |
Yes |
No |
Yes |
IIIb |
Non-inflammatory |
Yes |
No |
No |
|
IV |
Asymptomatic inflammatory prostatitis |
- Asymptomatic - No history of genitourinary pain complaints - Leukocytosis is present |
No |
No |
Yes |
Causes
UTI and STI pathogens
Signs and symptoms
- Fever
- Acute pain in the pelvis and perineum
- Dysuria and frequency
- Urinary retention or difficulty to void
- Acutely tender prostate on rectal examination
- Painful ejaculation
- Blood in the semen
Complications
- Bladder outlet obstruction
- Urinary retention
- Abscess formation
- Infertility
- Recurrent cystitis
- Pyelonephritis
- Renal damage
- Sepsis
Investigations
- Full blood count
- Blood cultures
- Urine analysis
- Urine microscopy, culture and sensitivity
Treatment objectives
- Alleviate symptoms
- Eradicate causative microorganisms
- Prevent recurrence
Non-pharmacological treatment
- Sitz baths may provide symptomatic improvement
- Increase fluid intake to 3 to 4 litres per day
Pharmacological treatment
Acute bacterial prostatitis
Four to eight weeks of prostate-penetrating antibiotic therapy is typically required
If there are features of associated urethritis (STI regimen):
Ceftriaxone IV
1gm twice daily stat
THEN
Ciprofloxacin oral
500mg twice daily for three to six weeks
OR
Ciprofloxacin IV
200mg every 12 hours until pain and fever subside
THEN
Ciprofloxacin oral
500 mg orally every 12 hours for 3-6 weeks
Chronic/relapse/persistent infection:
Ciprofloxacin oral
500 mg orally every 12 hours
Referral
Refer to a urologist if:
- There is no response to treatment
- Urinary retention present
- Prostatitis is chronic or relapsing