Acute Purulent Rhinosinusitis
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Bacterial infection with pus accumulation in one or more of the paranasal sinuses.
Investigations
- Anterior rhinoscopy – watery/purulent nasal discharge occasionally foul-smelling Nasal congestion
 - Plain Paranasal Sinuses X-ray (Water’s, Caldwell views) Mucosal thickening; air-fluid levels
 
Pharmacological treatment
| 
 Clinical Diagnosis  | 
 Antibiotic  | 
 Duration  | 
 Penicillin allergy  | 
 Comments  | 
| 
 Acute Rhino-sinusitis 
  | 
 Antibiotics should ONLY be prescribed in SEVERE infection as this condition can have a viral cause. 
  | 
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| 
 Acute Bacterial Rhinosinusitis (severe or persistent symptoms) 
  | 
 First line Amoxicillin/clavulanic acid oral 625mg every 8 hours 
 Second line Doxycycline oral 100mg every 12 hours  | 
 5 days  | 
 First line Clarithromycin oral 500mg every 12 hours 
 Second line Doxycycline oral 100mg every 12 hours  | 
 
  | 
| 
 Peri-orbital Cellulitis 
  | 
 Clindamycin IV 900mg every 8 hours 
 AND Ciprofloxacin oral 500mg every 12 hours 
 Oral Step down Clindamycin oral 450mg 4 times daily 
 AND Ciprofloxacin oral 500mg every 12 hours  | 
 2 weeks  | 
 Clindamycin IV 900mg every 8 hours 
 AND Ciprofloxacin oral 500mg every 12 hours 
 Oral step down Clindamycin oral 450mg 4 times daily 
 AND Ciprofloxacin oral 500mg every 12 hours  | 
 - IV to oral switch when clinically suitable (24 – 48hrs) 
  | 
Referral
Refer the following to ENT specialists
- Children with ethmoiditis presenting as an acute periorbital inflammation or orbital cellulitis must be hospitalized immediately.
 - Adults with pronounced symptoms despite treatment. If sinusitis of dental origin is suspected Recurrent sinusitis (>3 attacks in a year) or chronic sinusitis (duration of illness of >12 weeks)