Oesophagus Cancer

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Clinical Description

This is a malignant tumor of the esophagus. The risk of cancer of the esophagus is increased by long-term irritation of the esophagus, such as from smoking, heavy alcohol intake, and barrett esophagitis. The most common histological subtype in Malawi is squamous cell carcinoma.

 

Clinical Features

SIGNS AND SYMPTOMS

  • Unexplained dysphagia or odynophagia
  • Weight loss

Treatment 

Note: All patients who are not fit for above curative options and or have metastatic disease should be considered for:

  • Endoscopic stent placement
  • Feeding tube
  • Palliative chemotherapy
  • Palliative Radiotherapy

PHARMACOLOGIC

  • Cisplatin, Fluorouracil, Carboplatin, Paclitaxel, Gemcitabine, Capecitabine are options to choose from +/- Radiotherapy.