Treatment for Susceptible Tuberculosis (TB)
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TREATMENT OF SUSCEPTIBLE TB
- Susceptible TB is treated with first-line drugs: Rifampicin (R), Isoniazid (H), Ethambutol (E), Pyrazinamide (Z). The four oral drugs (RHZE) come as an FDC tablet.
- Patients should not be admitted in the ward or hospital for administration of TB drugs except where they are very sick or unable to walk.
- TB drugs should be provided on ambulatory basis in all facilities.
Dosages of FDC formulations of first line anti-TB drugs for adults
|
Body weight |
Initiation Phase (2 Months) |
Continuation Phase (4 Months) |
|
[RHZE] [R150/H75/Z400/E275] Number of tablets |
[RH] [R150/H75] Number of tablets |
|
|
30-37 Kg |
2 |
2 |
|
38-54 Kg |
3 |
3 |
|
55-74 Kg |
4 |
4 |
|
75 Kg and over |
5 |
5 |
Dosages of FDC formulations of first line anti-TB drugs for children
|
Body weight |
Initiation Phase (2 Months) |
Continuation Phase (4 Months) |
|
|
RHZ 75/50/150 number of tablets |
Ethambutol 100mg number of tablets |
RH 75/50 number of tablets |
|
|
4-7kg |
1 |
1 |
1 |
|
8-11kg |
2 |
2 |
2 |
|
12-15kg |
3 |
3 |
3 |
|
16-24kg |
4 |
4 |
4 |
|
25 +kg |
Takes Adult Formulation |
|
|
For more details refer to following MoH Guidelines:
- National Tuberculosis Control Program Manual (8th edition, 2018)