Notes on DR-TB Regimens

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Notes on DR-TB Regimens

• Scientific and programmatic evidence on the composition, effectiveness, safety, dosages and duration of treatment for DR-TB regimens is evolving. Please refer to the latest guidelines from the National TB and Leprosy Control Program during the course of implementation of these STGs
• For DR-TB patients without Fluoroquinolone (FQ) resistance, an all oral, shorter treatment regimen for 9-12 months, containing at least 4 active medications from Group A, B, and C
• can be used for both adults and children at programmatic level under Operational Research (OR) ground. Under this regimen, Linezolid is only used for the first two months.
• The Standardized shorter regimen for DR-TB patients without Fluoroquinolone (FQ) resistance for both adults and children: 2 Bdq-Lfx-Lzd-Cfz-Cs/4 Bdq -Lfx-Cfz-Cs /36 Lfx-Cfz-Cs. Delamanid to be used in place of Bedaquiline in children under six years.