Platelets

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PLATELETS 

  • A component obtained by centrifugation of fresh blood within 6 to 8 hours.
  • One unit of platelet concentrate increases the platelet count by 10,000 to 20,000/ul of blood.
  • Must be transfused immediately upon arrival. Platelets should never be stored in a refrigerator or blood bank or in the ward.
    • Decision to transfuse should be based on a combination of clinical and laboratory findings rather than empirical platelet levels.

 

Indications For Platelets Use

  • Bleeding due to thrombocytopenia because of defective platelet production such as aplastic anaemia or leukemia.
  • Increased consumption e.g., DIC
  • Dilutional effects e.g., in massive transfusion

All patients needing platelets need further investigations, please refer to Central Hospital.

Dose:

  • 1 unit per 10kg
  • For infants under 10 kg, 5ml/kg
  • Cross-matching is not required
  • Caution: platelet transfusion not usually indicated in ITP and TTP unless if patient is bleeding or undergoing invasive surgery

Side effects: 

  • Febrile, non-haemolytic and allergic reactions are common in patients receiving multiple transfusions.