Staphylococcal Scalding Skin Syndrome

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CLINICAL DESCRIPTION

Skin disease characterized by exfoliation or erosion of the skin as a result of its cleavage by toxins released from infecting bacteria. Lacks mucosal involvement and is not secondary to drugs.

Cause: Staph. Aureus

 CLINICAL FEATURESSIGNS AND SYMPTOMS

• Malaise, fever, irritability, sore throat
• Sloughing of skin leaving moist skin and varnish-like crusts
• Severe skin tenderness and erythema
• Skin wrinkling with flaccid bullae
• Scaling and desquamation

INVESTIGATIONS

• Diagnosis is usually clinical
• Blood culture to isolate offending bacteria

TREATMENT

• Replace fluids
• Analgesics
• Give Flucloxacillin or Cloxacillin 250 - 500 mg 6 hourly for 7 days or
• Ceftriaxone 1g IV daily for 5-7days