Sickle Cell Disease - Antibiotic prophylaxis in labour and puerperium

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Antibiotic prophylaxis in labour and puerperium

  • Ceftriaxone, IV/IM, 1 g daily for 72 hours 

Or

  • Amoxicillin + Clavulanic Acid, IV, 1.2 g stat.

Then 

  • Amoxicillin + Clavulanic Acid, oral, 625 mg 12 hourly for 72 hours

Referral Criteria

All patients with sickle cell disease with obstetric complications should be referred to a specialist for continuing care.