Premature Rupture of the Membranes - infection prevention

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Pharmacological treatment for Infection prevention

Infection Prevention

1st Line Treatment

Evidence Rating: [B]

  • Amoxicillin (Amoxycillin), oral, 500 mg 8 hourly for 7 days 

And 

  • Metronidazole, oral, 400 mg 8 hourly for 7 days 

2nd Line Treatment

Evidence Rating: [C]

  • Amoxicillin + Clavulanic Acid, oral, 625 mg - 1 g 12 hourly for 7 days

Infection Prevention – patients with penicillin allergy

  • Erythromycin, oral, 500 mg 6 hourly for 7 days

And 

  • Metronidazole, oral, 400 mg 8 hourly for 7 days 

Foetal lung maturation – for babies 28-34 weeks - See full Ghana STG for details